Pragmatism and Outcomes in Clinical Mycology Trials

Zoom link

https://us02web.zoom.us/j/83284989604?pwd=OzQzAxKg5l5kEjWkwTbYb4jJPUGnbG.1

Agenda

• Welcome and introductions 
• Scott Evans, MS, PhD (25 minutes)
  Professor Evans will focus on the Desirability of Outcome Ranking (DOOR) Paradigm
• Sean Ong, MBBS, MRCP (25 minutes)
  Dr. Ong will discuss clinician approaches to hierarchical endpoints and how these may be applied to clinical mycology
• Q&A/open discussion (10 minutes)

About the Speakers

Dr. Scott Evans is a Professor and Founding Chair of the Department of Biostatistics and Bioinformatics and the Director of the Biostatistics Center at Milken Institute School of Public Health of the George Washington University. He is the: Director of the Statistical and Data Management Center for the Antibacterial Resistance Leadership Group (ARLG) funded by NIAID/NIH; the PI of the Coordinating Center for the Exercise and Nutrition Interventions to Improve Cancer Treatment-Related Outcomes (ENICTO) in Cancer Survivors Consortium funded by the NCI/NIH, and the co-PI of the Data Coordinating Center of the Clamp OR Delay among neonates with Congenital Heart Disease (CORD-CHD) clinical trial funded by the NHLBI/NIH. He served as: the Guest Editor of a mini-Series on DSMBs for the NEJM Evidence; a member of an FDA Advisory Committee; and the past-President of the Society for Clinical Trials (SCT). He is a recipient of the Mosteller Statistician Award, the Zackin Distinguished Collaborative Statistician Award, the Founders Award from the American Statistical Association (ASA), an elected member of the International Statistical Institute (ISI), and is a Fellow of the ASA, SCT, and the Infectious Disease Society of America (IDSA).

Dr. Sean Ong is an infectious diseases physician and early-career clinical researcher based at the University of Toronto. He completed a joint PhD program with the University of Toronto and University of Melbourne, with a research focus on novel approaches toward optimizing the design and delivery of clinical trials in infectious diseases, with a focus on bloodstream infections. He is part of the SNAP and BALANCE+ clinical trial networks, and has research interests in clinical trial design, novel methodology, bloodstream infection, and antimicrobial stewardship.